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Tuesday, March 16, 2010

Cancer Risk Factors

The following are various types of cancer and their risk factors:

* Breast- Family history of breast cancer, late childbearing, childlessness, obesity.

* Bladder- Smoking (nearly half of cases), hair dye - bladder cancer is more common in men than women.

* Cervical- First intercourse at an early age, history of genital herpes, multiple sexual partners.

* Colorectal- Being over 50 with colon polyps or ulcerative colitis, high-fat, low-fiber diet and smoking and family history of these disorders or colon cancer.

* Leukemia- benzene, Exposure to radiation benzene and other chemicals.

* Lung- Smoking (83 percent of cases), radiation, exposure to asbestos and secondhand tobacco smoke.

* Lymphoma- Being 50 and more than 50, no other known risk factors.

* Oral- Smoking, heavy alcohol use and chewing tobacco.

* Pancreatic- high-fat diet, Smoking.

* Prostate- More than 80 percent of cases occur after 65, risk increases with age.

* Skin- family history of skin cancer, frequent sun exposure, Fair skin, severe sunburn in childhood.

* Uterine- Being post-menopausal with a history of infertility, ovulation failure or abnormal bleeding, hypertension, diabetes, and obesity.

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Sunday, March 14, 2010

Reduce Your Risk of Carpal Tunnel Syndrome

Carpal tunnel syndrome includes a number of conditions characterized by swelling, pain, tingling and weakness in the wrists and hands.

The National Women's Health Information Center says you can help prevent carpal tunnel syndrome by taking these precautions:

1. When you work at a computer, make sure your equipment is kept at an ideal height and distance, limiting strain on your hands and wrists. Also, keep your elbows near your sides as you type.
2. Take a break once an hour.
3. Scatter activities that require repetitive movements of the hands and wrists.
4. Gently stretch and bend your hands and wrists in the opposite direction from typical movements.
5. Keep your muscles warm while you work. Consider fingerless gloves if you work in a cold office.

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Tuesday, March 9, 2010

Kidney Donors Go On to Lead Long, Healthy Lives


Giving a kidney carries few health risks, with donors living just as long or sometimes even longer than those who don't donate, the largest study to date of donors has found.

Using data on more than 80,000 U.S. residents who donated a kidney between 1994 and 2009, researchers found that donors lived now as long as people who were matched for age, gender, ethnic background and other health and demographic factors but who did not donate a kidney.

The normal length of follow-up was more than six years, although researchers had more than 12 years of data on 10,000 donors, according to the analysis in the March 10 issue of the Journal of the American Medical Association.

"On average, if you compare someone who has donated and lives with one kidney and compare them to someone just like them who lives with two kidneys, there is no increased risk of mortality," said study author Dr. Dorry Segev, a transplant surgeon and director of clinical research in transplant surgery at Johns Hopkins University School of Medicine in Baltimore.

Each year, about 6,000 living donors in the United States have a kidney removed to save another. About half donate to save a blood relative, Segev said. The other half donate to a friend or loved one, such as a spouse. A small number, about 100 a year, donate a kidney to save a stranger's life, Segev said.

"People who donate kidneys are heroes," Segev said. "They take risks for the direct benefit of another person."

In the study, researchers examined data from the United Network for Organ Sharing (UNOS) national registry and compared it to data on more than 9,000 participants in the third National Health and Nutrition Examination Survey.

While kidney donation is very safe, it's not totally without risk, the researchers noted. About 25 donors died within 90 days of the operation, putting the risk of death at 3.1 per 10,000 donors compared to 0.4 per 10,000 people who did not donate.

Although the researchers did not specifically study cause of death, complications from kidney removal could include major bleeding, reactions to anesthesia or blood clots, similar to those that could occur with any surgery, Segev said.

Men had higher surgical mortality than women, and blacks were more likely to die than whites or Hispanics, as were donors with high blood pressure.

"There is a three in 10,000 chance you will die from the operation. That is a real risk," Segev said. "While the risk is not zero, it happens to be one of the safest operations you can ever possibly have."

For comparison, the risk of death following gallbladder removal, also measured to be among the safest operations, is 18 per 10,000.

One year following the donation, the risk of death among those who donated was the same as those who didn't donate. And beyond that, donors had a similar -- and even a bit lower -- risk of dying as those who didn't donate. Five years out, the risk of death was 0.4 per 10,000 donors and 0.9 per 10,000 non-donors. Twelve years out, the risk of dying was 1.5 per 10,000 donors and 2.9 per 10,000 non-donors, according to the report.

There are two likely reasons why some people with one kidney may live longer than those with two, said Dr. Matthew Cooper, chairman of the UNOS living donor committee and director of kidney transplant and clinical research at University of Maryland School of Medicine.

One enlightenment is that those who donate, knowing they have only one kidney, see a doctor more frequently and take better care of themselves. Another possibility is that donors go through a rigorous screening process, which may mean healthier people are selected to begin with, Cooper explained.

"This study reaffirms what many of us have read in the transplant literature and recognize in our own practices," Cooper said. "Kidney donation is a safe process in the hands of a responsible transplant center that values the long-term health of living donors."

Still, the study authors noted that it's important to continue to monitor and gather data on donors over the long term. The national registry includes health information only up to a year or two post-transplant. The researchers used the Social Security Death Master File to determine who died, but could not study quality of life or any other health issues that might have developed.

"In that long gap of time between one year and many decades after the surgery, we don't have a lot of information about what happens with living donors," Cooper said.

Previous research has also shown kidney donation to be overwhelmingly safe. A study published in 2009 in the New England Journal of Medicine tracked nearly 3,700 kidney donors from as far back as 1963 and found their life expectancy was the same as those who didn't donate.


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Monday, February 22, 2010

Gas Cooking Might Up Your Cancer patient Risk

Slaving over a hot stove -- make that a hot gas stove -- might raise your risk for certain types of cancer.

Researchers in Norway have found that cooking with gas produces more potentially destructive fumes than electric cooking.
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But, in a report published online Feb. 17 in Occupational and Environmental Medicine, they also point out that professional chiefs and cooks are more at risk than the normal at-home cook.

"The risk to average at-home cookers is low, at least under Norwegian conditions, where most homes have a kitchen exhaust fan," said study author Ann Kristin Sjaastad, who's with the industrial economics and technology management department in the division of health environment and security at the Norwegian University of Science and Technology in Trondheim. "Yes, professional chiefs/cooks are most at risk, but further studies are essential to estimate their risk level."

The International Agency for Research on Cancer has classified cooking fumes from frying at high temperatures as "probably carcinogenic." The fumes have been found to have polycyclic aromatic hydrocarbons (PAHs), heterocyclic amines, higher and mutated aldehydes, and fine and ultrafine particles.

Regardless of the level of risk, cooks should follow certain "safe cooking" guidelines, said Dr. Lisa Ganjhu, an presence physician in the division of gastroenterology and liver diseases at St. Luke's-Roosevelt Hospital in New York City.

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Wednesday, February 10, 2010

Scientists Realize How HIV Is Transmitted among Men

Aids symbol

Researchers report that they've discovered the origin of strains of the AIDS virus that affect gay and bisexual men.

"By knowing the origin of the transmitted virus, scientists may be able to expand new vaccines, vaginal microbicides and drugs to avoid the spread of sexually transmitted HIV," study author Dr. Davey Smith, an associate lecturer of medicine at the University of California San Diego.

At subject is the HIV in semen, which is made up of seminal cells and liquid called seminal plasma. HIV particles with RNA inside exist in the fluid, while the decisive cells hold the DNA of HIV, the study authors explained.

The researchers used a type of heritable analysis to study men who had sexually transmitted their HIV to other men.

"Until now, it had not been recognized whether HIV RNA or DNA is transmitted during sex," said Smith. "By analyzing the genetic differences between these two forms and the virus that was eventually transmitted to newly infected individuals; we found that it was the HIV RNA form present in seminal plasma that was transmitted."

What about HIV transmission to women? "Since the vast popular of women are infected with HIV by exposure to the virus in semen, HIV RNA in the seminal plasma is the possible culprit, but this needs to be confirmed.

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Monday, February 1, 2010

Long Ahead of Symptoms, Blood May Reveal Rheumatoid Arthritis

A blood test can forecast rheumatoid arthritis long before a person notices symptoms, say Swedish researchers.

They identified several cytokines, cytokine-related factors and chemokines whose stages increase significantly as much as various years before the onset of rheumatoid arthritis (RA).

People who receive an early and accurate diagnosis of RA and directly begin treatment are more likely to lead an active life and less probable to suffer joint damage that leads to joint replacement, according to the American College of Rheumatology.

In the study, the researchers analyzed blood samples taken from 86 people before the onset of RA symptoms, from 69 of the same people after RA symptoms began and from a group of 256 people who did not have the disease.

The blood samples were checked for levels of 30 cytokines, related factors and chemokines. The main variation detected between people who later developed RA and those who did not have it was the presence of Th1 cell-, Th2 cell-, and Treg cell-related cytokines. The main difference among people before and after development of RA was the presence of chemokines, stromal cell-derived cytokines and angiogenic-related markers.

The elevated concentrations of proinflammatory cytokines, cytokine-relevant factors and chemokines indicate immune system activation before any symptoms of RA-related joint problems.

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Friday, January 29, 2010

Your Body Moves During Time With Your Mind

Human brainWhen people imagine back to the past or look in the direction of the future, their body language reflects their intelligence of time travel, a new study suggests. Researchers at the University of Aberdeen fixed subjects with motion sensors and asked them to imagine events in the hope or the past. The bodies of those who idea about the future actually moved forward. Those who thought about the past swayed backward.
The findings emerge online in the journal Psychological Science.

The embodiment of time and space yields an overt behavioral marker of an otherwise invisible mental operation.

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