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Pharmacy home >> Dentistry Articles >> Listerine
Listerine
Listerine is a brand name for antiseptic mouthwash,
named after Joseph Lister (father of modern antiseptics). Its
medicinal taste is palliated slightly by a sweet flavor. Its
slogan is, "Kills germs that cause bad breath", though
there is no evidence to suggest it cures halitosis.
Currently manufactured and distributed by Pfizer
Inc, Listerine is one of the most popular mouthwashes (Scope
being its main competitor).
The active ingredients are menthol, thymol,
methyl salicylate, and eucalyptol, all of which are structural
isomers. While not listed as an active ingredient, ethanol or
grain alcohol is present in concentrations between 21 and 26%
w/v. This accounts for a large part of Listerine's antibiotic
activity. Currently, other types of Listerine include Cool Mint,
FreshBurst, Natural Citrus, Tartar Control, and Whitening.
The Listerine brand name is also used on brands
of toothpaste, and PocketPaks, a minty, dissolvable strip intended
to instantly wash and refresh the mouth.
History
Advertising too is a brilliant tool for creating
conventional wisdom. Listerine, for instance, was invented in
the nineteenth century as a powerful surgical antiseptic. It
was later sold, in a distilled form, as a floor cleaner and
a cure for gonorrhea. But it wasn't a runaway success until
the 1920s, when it was pitched as a solution for "chronic
halitosis"--a then obscure medical term for bad breath.
Listerine's new ads featured forlorn young women and men, eager
for marriage but turned off by their mate's rotten breath. "Can
I be happy with him in spite of that?" one maiden asked
herself. Until that time, bad breath was not conventionally
considered a catastrophe. But Listerine changed that. As the
advertising scholar James B. Twitchell writes, "Listerine
did not make mouthwash as much as it made halitosis." In
just seven years, the company's revenues rose from $115,000
to more than $8 million.
(from Freakonomics, 91)
Cancer controversy
There is no evidence that its properties as
a solvent, mainly because of the 26.9% (in regular Listerine)
alcohol, causes an easier reception of carcinogens. In other
words, repeated use of Listerine does not increase the chance
of oral cancer. Both the American Dental Association (ADA) and
the United States National Cancer Institute (NCI) agree that
the alcohol contained in antiseptic mouthrinse is safe and not
a factor in oral cancers. Specific study reviews and results
can be found in clinical reports by J.G. Elmore and R. I. Horowitz
[Oral cancer and mouthwash use: Evaluation of the epidemiologic
evidence. Otolaryngol Head Neck Surg. 1995;1(113):253-261] and
Mashburg et al. [A Study of the relationship between mouthwash
use and oral and pharyngeal cancer. JADA. 1985.] which summarize
that alcohol-containing mouthrinses are not associated with
oral cancer.
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