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Amelogenesis is the formation of enamel on teeth and occurs after dentinogenesis, which is the formation of dentin. Since dentin must be present for enamel to be formed, this prerequisite is an example of the biologic concept, termed reciprocal induction.

Amelogenesis begins in the crown stage of tooth development and is considered to have two stages. The first stage is known as the secretory phase, and the second stage is known as the maturation stage.