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Home  List of Disease  Acute intermittent porphyria

Disease Name:Acute intermittent porphyria
Acute intermittent porphyria
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Treatment:A high-carbohydrate diet is typically recommended; in severe attacks, a glucose 10% infusion is recommended, which may aid in revival. If drugs have caused the attack, discontinuing the offending substances is essential. Infection is one of the top causes of attacks and requires vital treatment. Pain is extremely severe and almost always requires the use of opiates to reduce it to bearable levels.
Description:Acute intermittent porphyria (AIP) is a rare autosomal dominant metabolic disorder disturbing the production of heme, the oxygen-binding prosthetic group of hemoglobin. It is characterized by a lack of the enzyme porphobilinogen deaminase. Acute intermittent porphyria is the second most common form of porphyria.

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