Acrocephalosyndactyly may be an autosomal dominant disorder.
Surgery is required to prevent the closing of the coronal sutures from damaging brain growth.
Apert syndrome is a figure of acrocephalosyndactyly, a congenital disorder characterized by malformations of the skull, face, hands and feet. It is classified as a branchial arch syndrome, affecting the first branchial (or pharyngeal) arch, the ancestor of the maxilla and mandible. Disturbances in the growth of the branchial arches in fetal development create lasting and widespread effects.